We are undertaking research to look at the events that occur during conception and early pregnancy to improve pregnancy rates for women who struggle to conceive and improve health outcomes for babies in general.
Of particular interest to us is Polycystic Ovarian Syndrome. This syndrome not only causes difficulties in becoming pregnant but is associated with an increased risk of diabetes and cardiovascular disease in later life. We are working to understand PCOS better and improve treatment and diagnosis.
Flagposts for fertility
The short video below explains how our research can be translated into tests that help to plan the IVF process.
Understanding Successful Embryo Implantation
Most pregnancies fail before they can be clinically verified, which is before the embryo implants into the lining of the womb, 7-9 days after fertilisation. Learning more about how this embryo develops and emits signals using hormones helps us understand why embryos are more likely to implant successfully as part of the IVF process.
Genesis Research Trust is funding Tommy Mau’s research at Imperial College London into how lipids (fatty substances) control energy storage and produce signals during embryonic development. His studies have shown that lipid droplets can actively increase their size – increasing fat storage capacity – and develop the embryo’s tissues in readiness for implantation.